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| Tirzepatide 5 mg | Tirzepatide 10 mg | Tirzepatide 15 mg | Placebo | |
|---|---|---|---|---|
|
A1C reduction from baseline of 7.9% |
Tirzepatide 5 mg:
-1.87% |
Tirzepatide 10 mg:
-1.89% |
Tirzepatide 15 mg:
-2.07% |
Placebo:
+0.04% |
|
Placebo-adjusted A1C reduction |
Tirzepatide 5 mg:
-1.91% |
Tirzepatide 10 mg:
-1.93% |
Tirzepatide 15 mg:
-2.11% |
Placebo:
N/A |
|
Weight reduction from baseline of 85.9 kg |
Tirzepatide 5 mg:
-7.0 kg (-7.9%) |
Tirzepatide 10 mg:
-7.8 kg (-9.3%) |
Tirzepatide 15 mg:
-9.5 kg (-11.0%) |
Placebo:
-0.7 kg (-0.9%) |
|
Placebo-adjusted weight reduction |
Tirzepatide 5 mg:
-6.3 kg |
Tirzepatide 10 mg:
-7.1 kg |
Tirzepatide 15 mg:
-8.8 kg |
Placebo:
N/A |
|
Percent of participants achieving A1C <7% |
Tirzepatide 5 mg:
86.8% |
Tirzepatide 10 mg:
91.5% |
Tirzepatide 15 mg:
87.9% |
Placebo:
19.6% |
|
Percent of participants achieving A1C <5.7% |
Tirzepatide 5 mg:
33.9% |
Tirzepatide 10 mg:
30.5% |
Tirzepatide 15 mg:
51.7% |
Placebo:
0.9% |
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